14 citations
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January 2014 in “Cells Tissues Organs” This study found that single high-dose irradiation in mice induced more severe acute skin injury and hair depigmentation, while fractional doses led to longer-term damage in the dermis and subcutis.
19 citations
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February 2017 in “Journal of radiation research” This study found that high-dose radiation can induce accelerated cellular senescence, inflammation, and loss of epithelial stem cells in mouse and human skin, contributing to radiation dermatitis.
May 2023 in “Current Applied Science and Technology” In this animal study, researchers found that exposure to a CO2 laser at various power levels caused significant skin damage in rats, including severe burns, coagulation, and tissue obliteration, with higher laser doses resulting in more pronounced injuries.
5 citations
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September 2019 in “Journal of Biomedical Optics” This study determined in-vivo skin damage thresholds for 1319-nm laser exposure in pigs, and the findings may enhance understanding of thermal damage mechanisms and inform laser safety standards.
13 citations
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January 1963 in “Radiation Research” This study observed that in mice, small-scale x-ray irradiation resulted in uniquely rapid healing of hair follicles, differing from the hypertrophic and hyperplastic responses seen in larger irradiated areas.