Hair Straightening and Acute Kidney Injury: A Case Series from a Medical Toxicology Service

    August 2025 in “ Clinical Toxicology ”
    Yuval Rabinovich, Dennis Scolnik, Ayelet Rimon … Miguel Glatstein
    Studysummary This study suggests an association between glyoxylic acid-containing hair-straightening treatments and acute kidney injury in young women, with urine calcium oxalate crystals observed in some cases, indicating potential nephrotoxicity. Early treatment with thiamine and pyridoxine may mitigate the severity of kidney damage.
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    Research cited in this study 4

    1. Straight to the Point: What Do We Know So Far on Hair Straightening? Skin appendage disorders · 2021
    2. Formaldehyde Replacement with Glyoxylic Acid in Semipermanent Hair Straightening: A New and Multidisciplinary Investigation International Journal of Cosmetic Science · 2014
    3. An Overview of Chemical Straightening of Human Hair: Technical Aspects, Potential Risks to Hair Fiber and Health, and Legal Issues International Journal of Cosmetic Science · 2013
    4. Progressive Hair Straightening Using an Automated Flat Iron: Function of Silicones PubMed · 2013