Hair Regeneration After Epidermal Peeling
April 2020
in “
European Journal of Dermatology
”
Studysummary This study reported that apremilast treatment did not lead to sustained improvement in SALT scores for most patients with extensive and treatment-resistant alopecia areata.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
The study explored the concept of "wound-induced hair follicle neogenesis" (WIHN), where a large open full-thickness wound of skin was shown to induce hair follicle regeneration in adult mice. This process was particularly relevant in the context of androgen alopecia (AGA), where the telogen-anagen transition in hair follicles fails, leading to blocked hair regeneration and baldness. The research suggested that epidermal peeling might stimulate hair regeneration by overcoming the incomplete transition phase in AGA-affected regions.
