Assessment of Hair Loss and Skin Changes During Treatment in Asian Breast Cancer Patients: A Prospective Cohort Study

This study evaluated hair loss and skin changes in 322 Asian breast cancer patients, comparing effects based on treatment regimens. Patients were assessed one day before and 6 months after surgery. Those receiving taxane-based chemotherapy in the adjuvant treatment group experienced significantly higher odds of increased hair loss, a higher melanin index, and more wrinkles. In contrast, hair loss was reversed in most patients in the neoadjuvant treatment group 6 months post-surgery. The study emphasizes the importance of informing patients about these potential side effects and providing supportive care to improve their quality of life.