17 citations
,
November 2013 in “American Journal of Primatology” This study reported species and demographic differences in alopecia rates among macaques, with the highest rates in pigtail macaques and noted age-related improvements in alopecia scores.
119 citations
,
August 2010 in “Journal of Investigative Dermatology” This study reports that 11β-HSD1 activity in human skin increases with age and photoexposure, potentially contributing to skin aging and the effects of glucocorticoids.
18 citations
,
June 2010 in “Cell Stress and Chaperones” This study reported that heat treatment significantly increased the incidence of alopecia areata in C3H/HeJ mice, suggesting a role for induced HSPA1A/B expression in disease development.
23 citations
,
January 2010 in “Journal of Medical Primatology” This study found that alopecia in captive Rhesus macaques may be linked to chronic hypersensitivity dermatitis with CD4+ cell inflammation, possibly influenced by altered housing and reduced pathogen exposure.
87 citations
,
February 2009 in “PubMed” This review discusses the potential causes and treatments for alopecia in nonhuman primates, emphasizing the need for comprehensive testing before attributing hair loss to stress.
16 citations
,
September 2008 in “American Journal of Orthodontics and Dentofacial Orthopedics” This article reports a case of pressure alopecia caused by wearing headgear, emphasizing the importance of early diagnosis to prevent potential scarring.
31 citations
,
April 2007 in “Experimental Dermatology” This study found that foot shock stress prolonged the telogen stage and delayed anagen induction in the hair cycle of non-depilated mice, potentially through stress-induced actions of substance P.
51 citations
,
November 2005 in “Journal of Medical Primatology” This study observed that hair loss in captive rhesus macaques varies with season, sex, and housing conditions, and is significantly correlated with HPA axis activity as indicated by faecal cortisol metabolites.
489 citations
,
June 2005 in “The FASEB Journal” This study found that human scalp hair follicles can respond to corticotropin releasing hormone stimulation similarly to the classical HPA axis, including up-regulating cortisol production and activating neuroendocrine feedback loops.
75 citations
,
January 1995 in “American journal of primatology” In this study, seasonal hair loss was most pronounced in low-ranking male vervet monkeys, and changes in scrotal color and hyperpigmentation also correlated with hair loss, but underlying causes were not identified.
70 citations
,
March 1980 in “Journal of Nutrition” Zinc deficiency in monkeys causes skin issues and reproductive problems, but supplementation reverses these effects.