Hair Greying in Castrated Mice

    September 2022 in “ F1000Research ”
    Aoi Matsumoto, Junko Kawabe, Natsumi Kawakami, Koichi Node, Makoto Akashi
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    TLDR Removing hair from mice without reproductive glands led to grey hair, possibly helping to understand greying in aging.
    The research conducted by Yamaguchi University and Saga University in Japan involved 94 mice and found that hair plucking caused hair to grey in castrated mice, a process that continued for several hair cycles. The study suggests that the decrease in androgen secretion, which happens with age in both genders, may contribute to age-related hair greying. The researchers also proposed that this method could be used to create a new mouse model for studying hair greying without the need for genetic engineering.
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