Hair Follicle Stem Cells Provide a Functional Niche for Melanocyte Stem Cells

February 2011 in “ Cell stem cell ”

Shintaro Tanimura, Yuko Tadokoro, K Inomata, Nguyễn Thanh Bình, Wataru Nishie, Satoshi Yamazaki, Hiromitsu Nakauchi, Yoshio Tanaka, James R. McMillan, Daisuke Sawamura, Kim B. Yancey, Hiroshi Shimizu, Emi K. Nishimura

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Research cited in this study

7 / 7 results

research Disruption of Smad4 in Mouse Epidermis Leads to Depletion of Follicle Stem Cells

43 citations , December 2008 in “Molecular biology of the cell”

Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.

research Stem Cells and Their Niches

1549 citations , March 2006 in “Science”

Understanding stem cell interactions with their environments is key for advancing regenerative medicine.

research Deregulated expression of c-Myc depletes epidermal stem cells

315 citations , June 2001 in “Nature Genetics”

research C-Myc Activation in Transgenic Mouse Epidermis Results in Mobilization of Stem Cells and Differentiation of Their Progeny

338 citations , April 2001 in “Current Biology”

c-Myc activation in mouse skin increases sebaceous gland growth and affects hair follicle development.

research Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells

949 citations , January 2001 in “Cell”

Adult mouse skin contains stem cells that can create new hair, skin, and oil glands.

research The Biology of Hair Follicles

1113 citations , August 1999 in “The New England Journal of Medicine”

Hair follicle biology advancements may lead to better hair growth disorder treatments.

research Generalized atrophic benign epidermolysis bullosa.

51 citations , January 1997 in “PubMed”

GABEB is a less severe skin condition caused by a gene mutation affecting collagen, leading to blisters and other symptoms.

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Casein Kinase 1 Inhibition in Keratinocytes Enhances the Migration of Melanocyte Precursors in the Hair Follicle via KitL/c-Kit Signaling Pathway

research Casein Kinase 1 Inhibition in Keratinocytes Enhances the Migration of Melanocyte Precursors in the Hair Follicle via KitL/c-Kit Signaling Pathway

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Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.

research Functionally Distinct Melanocyte Populations Revealed by Reconstitution of Hair Follicles in Mice

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Only skin melanocytes, not other types, can color hair in mice.

research Aging of the Hair Follicle Pigmentation System

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Hair grays due to oxidative stress and fewer functioning melanocytes.