On Hair Follicle Development and Wool Production Traits in Sheep: A Review

January 2020 in “ International journal of agriculture & biology/International journal of agriculture and biology ”

Sun Wu, MA Shi-ke, Yahong Ma

hair follicle skin development genes histomorphology molecular mechanisms

Studysummary This review examines the development and molecular mechanisms of hair follicle and wool traits in sheep, but reports no new results, aiming to support breeding and selection strategies.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer ·

The review discussed the complex biological processes and regulatory molecules involved in hair follicle and skin development in sheep. It highlighted that wool traits are controlled by multiple genes and influenced by environmental factors. The paper aimed to provide a theoretical basis for breeding and selecting sheep for desirable wool traits by examining the histomorphology and molecular mechanisms of hair follicle development.

View this study on doi.org →

Discuss this study in the Community →

Similar Research

5 / 1000+ results

research Comprehensive analysis of the expression profiles of mRNA, lncRNA, circRNA, and miRNA in primary hair follicles of coarse sheep fetal skin

13 citations , June 2024 in “BMC Genomics”

This study found distinct expression patterns of various transcription types during hair follicle morphogenesis, providing a foundation for understanding hair development mechanisms and aiding selective breeding for desirable wool traits in a specific breed.

research TMT-based quantitative proteomics reveals the genetic mechanisms of secondary hair follicle development in fine-wool sheep

2 citations , February 2025 in “PLoS ONE”

This study used TMT-based quantitative proteomics to analyze the development of secondary hair follicles in fetal sheep, revealing increased follicle density and key proteins involved, such as COL1A1 and THBS4, indicating their potential role in wool quality traits.

research Unlocking the genetic secrets of Dorper sheep: insights into wool shedding and hair follicle development

December 2024 in “Frontiers in Veterinary Science”

This study on Dorper sheep identified important genetic factors influencing hair follicle development, finding that expression patterns and genes like DBI, FZD3, and ZDHHC21 play a crucial role in wool shedding, which could help improve understanding of mammalian skin-related traits and human hair advancement.

research Integrated Analysis of miRNAs and mRNA Profiling Reveals the Potential Role of miRNAs in Sheep Hair Follicle Development

July 2022 in “Research Square (Research Square)”

This study found that miR-23b and miR-133 significantly reduce mRNA and protein levels of specific target genes involved in Merino sheep hair follicle development, providing insight into molecular breeding for fine wool production.

research Novel Insights to Assess Climate Resilience in Goats Using a Holistic Approach of Skin-Based Advanced NGS Technologies

June 2023 in “International journal of molecular sciences”

In this study, researchers observed that heat stress significantly affected hair and skin traits in two indigenous goat breeds, with Kodi Aadu goats demonstrating greater thermal resilience compared to Kanni Aadu goats, potentially due to differences in gene expression and methylation.