Genome-Wide Scan and Fine-Mapping Linkage Study of Androgenetic Alopecia Reveals a Locus on Chromosome 3q26

March 2008 in “ American Journal of Human Genetics ”

Axel M. Hillmer, Antonia Flaquer, Sandra Hanneken, Sibylle Eigelshoven, Anne-Katrin Kortüm, Felix F. Brockschmidt, Astrid Golla, Christine Metzen, Holger Thiele, Susanne Kolberg, Roman Reinartz, Regina C. Betz, Thomas Ruzicka, Hans Christian Hennies, Roland Kruse, Markus M. Nöthen

androgenetic alopecia AGA genetic loci chromosome 3q26 genetic factors male pattern baldness

TLDR Hair loss gene found on chromosome 3q26.

This study conducted a genome-wide scan and fine-mapping linkage study to identify genetic loci associated with androgenetic alopecia (AGA). The study found evidence for multiple genes contributing to AGA susceptibility, with a significant locus identified on chromosome 3q26. The study suggests that genetic factors play a significant role in the development of AGA. The study provides a first step towards identifying new genes contributing to the development of early onset AGA.

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