Genetic Basis of Pigmentation and Its Disorders

    Lawrence E. Klein, James J. Nordlund
    TLDR Understanding genes can help diagnose and treat skin color disorders.
    The document "Genetic Basis of Pigmentation and Its Disorders" discussed the genetic factors influencing skin pigmentation and related disorders. It highlighted the role of various genes in determining pigmentation and how mutations or alterations in these genes could lead to conditions such as albinism and vitiligo. The study emphasized the importance of understanding these genetic mechanisms to develop better diagnostic and therapeutic approaches for pigmentation disorders. The research was supported by grants from the Veterans Administration and the NIH, indicating a significant investment in understanding these dermatological issues.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community 11 months on fin + min. Thoughts?

      in Progress Pictures  913 upvotes 2 months ago
      A user shared progress pictures after 11 months on finasteride and minoxidil, with intermittent microneedling. The community responded positively, noting significant hair regrowth and encouraging continued treatment.

      community As step up from scalp micro pigmentation

      in Satire  342 upvotes 1 year ago
      The conversation is about someone using finasteride and minoxidil along with microneedling as a treatment for hair loss, and there's a mention of scalp tattooing as an alternative or additional approach. Some responses mock the approach, while others inquire about the specifics of the treatment and its effectiveness.

      community 24 weeks of treatment. Best decision of my life

      in Progress Pictures  880 upvotes 3 days ago
      A 32-year-old male used 1.25mg oral finasteride daily and 1ml topical minoxidil twice daily for 24 weeks, experiencing improved skin and hair growth with initial side effects that resolved after three weeks. He plans to try dermastamping to address a stubborn cowlick area.

      community Hair Tattoo as a substitue to hair transplant

      in Transplants  517 upvotes 1 year ago
      A hair tattoo substitute for a hair transplant, which many people felt was not a good idea. Several treatments were suggested as alternatives, such as Scalp Micro Pigmentation (SMP) and wigs.

      community Fighting Hair loss AND Grey Hair

      in Treatment  18 upvotes 2 years ago
      The user is treating hair loss with topical Minoxidil, Finasteride, RU58841, microneedling, and Ketoconazole. For grey hair, they use L-Cysteine, L-Methionine, and PABA, and have noticed some re-pigmentation.

    Similar Research

    5 / 1000+ results
      Melanocytes and Vitiligo and Hair Graying

      research Melanocytes and Vitiligo and Hair Graying

      1 citations, January 2014 in “Elsevier eBooks”
      Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.
      Index

      research Index

      November 2019 in “Harper's Textbook of Pediatric Dermatology”
      The document is a detailed medical reference on skin and genetic disorders.
      Melanocytes: The New Black

      research Melanocytes: The New Black

      93 citations, October 2006 in “The International Journal of Biochemistry & Cell Biology”
      Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.