Female Androgenetic Alopecia Among Market Women in Lagos, Nigeria

A woman with androgenetic alopecia is using a treatment of topical finasteride with 7% minoxidil, spironolactone, and supplements like iron, vitamin D, biotin, and zinc. She is considering additional treatments like PRP and laser therapy but has not seen significant hair regrowth yet.

Dutasteride at 0.5 mg/day does not significantly alter allopregnanolone levels, but higher doses (2.5 mg/day) do. Dutasteride may also have anti-neuroinflammatory effects, but the impact on neurosteroids is still debated.

Dutasteride significantly improved hair health and reduced shedding for a woman with PCOS and hyperandrogenism, without causing depression or anxiety, unlike finasteride. Dutasteride also helped with PMDD symptoms and had no side effects, though it changed hair texture.

The user achieved significant hair regrowth using dutasteride 0.5mg for a year and oral minoxidil 2.5mg for eight months, despite initial shedding. They reported no side effects and preferred oral treatments over topicals.