Sweat Under Surveillance: Loss of Immune–Metabolic Loop During Aging

June 2026 in “ Journal of Investigative Dermatology ”

C P Lu

eccrine sweat glands dendritic cells sweat gland clear cells NAMPT–INSR signaling NAD+ supplementation MIF–CD74 antagonists hypohidrosis immune–metabolic interactions sweat glands DCs SGCs NAD+ MIF antagonists

Studysummary Aging weakens sweat glands due to reduced support from immune cells, but treatments may help restore function.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer ·

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