And Next… Adnexa: Frontal Fibrosing Alopecia

    Joana Cabete, André Lencastre
    Image of study
    TLDR A 55-year-old woman with several health conditions did not see hair regrowth after a transplant.
    In 2015, a 55-year-old African woman with a medical history of type 2 diabetes, hypothyroidism, hypertension, and depression sought medical attention for a 4-year history of frontotemporal alopecia and complete loss of eyebrows. She experienced scalp itching and occasionally developed red bumps on her limbs. Despite undergoing hair transplantation a year prior, she saw no improvement in her hair loss. Her medications included metformin for diabetes, levothyroxine for hypothyroidism, amlodipine for hypertension, and sertraline for depression. No other treatments for her hair loss had been attempted at the time of the report.
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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 5 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Fibrosing alopecia in a pattern distribution

      in Research/Science  14 upvotes 10 months ago
      A user has been experiencing hair loss for 4 years, with treatments like minoxidil, finasteride, and various supplements proving ineffective. They were diagnosed with fibrosing alopecia in a pattern distribution, a condition that may require a combination of anti-inflammatory and hair growth treatments.

      community almost 6 months of progress :)

      in Progress Pictures  532 upvotes 1 month ago
      The user shared their 6-month hair regrowth progress using finasteride, minoxidil, biotin, and iron supplements, along with occasional microneedling and specific shampoos. They reported minimal side effects and no retrograde alopecia, attributing their success to a combination of treatments.
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      community Where to Begin with Microneedling?

      in Treatment  17 upvotes 1 year ago
      User is considering microneedling to enhance hair regrowth after limited response to minoxidil and better results with finasteride and ketoconazole shampoo. Recommendations include using a 1.5mm derma roller once a week, avoiding minoxidil on microneedling days, and disinfecting the roller with isopropyl alcohol.

      community How essential is scalp biopsy when dealing with hair loss?

      in Treatment  6 upvotes 3 months ago
      The user experienced hair loss despite using Fin and Min for 12 years and switched to Dutasteride, RU58841, and Keto scalp serum, but shedding and itch persist. They are considering increasing Dutasteride to 2.5mg and questioning the necessity of a scalp biopsy, with mixed opinions on its usefulness.

      community We Need A Solution For The Inflammatory Response related To AGA

      in Research/Science  16 upvotes 5 months ago
      The conversation is about finding a solution for scalp inflammation related to AGA, with the user expressing frustration that Minoxidil and Finasteride do not address inflammation. The user has researched glucocorticoids and topical NSAIDs for reducing inflammation and seeks advice from specialists.

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