Fractional CO2 Laser Versus Microneedling Followed by Topical 5-Fluorouracil in the Treatment of Non-Segmental Vitiligo

    TLDR Combining either fractional CO2 laser or microneedling with 5-FU is more effective for treating vitiligo.
    The study compared the effectiveness of two treatments for non-segmental vitiligo in 30 patients: fractional CO2 laser followed by topical 5 Fluorouracil (5-FU) and microneedling followed by 5-FU. The results indicated that combining either the FrCO2 laser or microneedling with 5-FU is a more effective and safe approach for treating vitiligo than using either method alone. This combination offers a new therapeutic window for patients with vitiligo.
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