TLDR Flutamide effectively treated hair growth and related symptoms in women, with common side effects like dry skin and hot flushes.
The study demonstrated that flutamide, at a dosage of 250mg twice daily, was effective in treating moderate to severe hirsutism, as well as associated symptoms such as acne, seborrhoea, and androgenetic alopecia in women. The treatment lasted for one year and included 20 women, 18 of whom also received an oral contraceptive unless they had a tubal ligation. Flutamide was rapidly successful in 19 of the 20 patients, with one patient requiring additional treatment with a gonadorelin analogue. Notably, 12 of these patients had not responded to previous treatments, which included oral contraceptives, spironolactone, and dexamethasone. The most common side effects reported during the study were dry skin (70% of patients), hot flushes (27%), and increased appetite (25%).
January 1983 in “Elsevier eBooks” Cyproterone acetate is used to treat conditions like prostate cancer, early puberty, excessive sexual drive, and female androgenization by affecting androgen functions and suppressing certain hormones.
70 citations,
January 2000 in “Hormone Research in Paediatrics” SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.
99 citations,
December 2010 in “Journal of The European Academy of Dermatology and Venereology” The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.
5 citations,
January 2014 in “Current Dermatology Reports” Many adult women suffer from persistent or late-onset acne, and while various treatments exist, finding the right one can be challenging.
26 citations,
August 2008 in “Clinical endocrinology” The document concludes that more multidisciplinary research is needed to understand and treat PCOS, a condition that significantly affects women's health and quality of life.
