Effects of Recombinant Human Keratinocyte Growth Factor-2 on Hair Regeneration in Experimental Bald Rats

The study aimed to evaluate the effects of recombinant human keratinocyte growth factor-2 (rhKGF2) on hair regeneration in experimentally bald SD rats. The rats were divided into seven groups and treated with different substances, including rhKGF2 at various doses. Results showed that rhKGF2 significantly improved hair length and weight compared to the saline group, with the high and middle doses showing the most notable effects. Histological examination confirmed that rhKGF2 promoted the formation and maturation of hair follicles. The study concluded that rhKGF2 played a significant role in hair regeneration and had promising potential for clinical application.