The Study on Functional Effects for Hair Loss Prevention Using Astringent Persimmon Fruit Extracts

In 2020, a study was conducted to investigate the hair restoration efficacy of astringent persimmon fruit extracts on a genetically predisposed to balding pattern Black mice model. The mice were treated with a water extract of astringent persimmon fruit (10 mg/mouse/day) daily until the completion of two full hair growth generations. The results showed that the hair existing area and hair length significantly increased (P > 0.001) in the mice treated with astringent persimmon fruit compared to the control mice. However, the number of hair follicles did not remarkably increase after the treatment. The data suggested that the topical application of astringent persimmon fruit may promote hair growth by extending the hair existing area and increasing hair length, which is an indicator of a prolonged anagen phase.