Effect of 150 kHz Electromagnetic Radiation on the Development of Polycystic Ovaries Induced by Estradiol Valerate in Sprague Dawley Rats

    December 2020 in “ Research Square (Research Square)
    Stephanie Mohammed, Venkatesan Sundaram, Nikolay Zyuzikov
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    Studysummary This study suggests that 150 kHz electromagnetic radiation exposure may reduce follicular cysts and increase developing follicles in a rat model of polycystic ovaries without affecting hormonal levels or overall ovary morphology. Our plain-language summary of this paper — not a Tressless recommendation.
    The study investigated the effect of 150 kHz Electromagnetic Radiation (EMR) on polycystic ovary syndrome (PCOS) in rats. Twenty-one female rats were divided into three groups: control, Estradiol Valerate (EV), and EV + EMR. The EV + EMR group was exposed to 150 kHz EMR for eight weeks. The body and ovary weights did not significantly differ between the EV and EV + EMR groups. The estrous cycle was irregular in both the EV and EV + EMR groups. However, the ovarian histology showed near-normal morphology with little or no degenerative changes in the developing follicles in the exposed group. There was an increased number of developing follicles and a significant reduction in the number and size of follicular cysts in the EV+EMR group. Hormonal analysis showed no significant difference in testosterone and FSH levels between the EV+EMR and EV groups, but the LH and LH/FSH ratio decreased significantly in the EV+EMR group. The study concluded that 150 kHz EMR appears to have a positive effect on PCOS, reducing the number and size of follicular cysts and causing little or no degenerative changes in developing follicles.
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