Assessment of Dysregulation of HERC6 and Essential Biological Processes in Response to Laser Therapy of Human Arm Skin

The 2020 study investigated the role of the gene HERC6 in response to CO2 laser therapy on human skin. The researchers analyzed 16 gene expression profiles before and after treatment, finding that HERC6 and its neighboring genes played a significant role in response to the laser. They identified 27 out of 52 significant differentially-expressed genes (DEGs) as critical in response to laser irradiation. The study concluded that HERC6 and its first neighbors are involved in essential cellular responses to laser therapy, affecting various parts of the cell and regulating several essential biological processes. This suggests that more safety considerations are needed due to the broad impact of laser treatment at the cellular level.