Docetaxel-Induced Psoriasis: A Case Report

In a letter to the editor, the authors reported a case of docetaxel-induced psoriasis, a side effect not previously associated with the chemotherapy drug docetaxel. The patient, a 65-year-old man with squamous cell carcinoma of the lung, developed psoriasis-like lesions on his trunk and limbs after starting treatment with docetaxel. Despite having no known drug allergies and no personal history of psoriasis (though his brother had the condition), the patient's symptoms appeared eight days following the first cycle of docetaxel and recurred with subsequent cycles. A biopsy confirmed the diagnosis, showing features consistent with psoriasis. The patient responded well to topical corticosteroids and calcipotriol. This case was considered significant as it was the first reported instance of generalized psoriasis following treatment with docetaxel, a drug with a broadening range of indications for various cancers. The authors did not declare any conflicts of interest.