Prevalent Decrease of the EGF Content in the Periurethral Zone of BPH Tissue Induced by Treatment with Finasteride or Flutamide

    September 1997 in “ PubMed ”
    Sara Monti, F. Sciarra, M.V. Adamo … Franco Di Silverio
    Studysummary This study found that Finasteride treatment significantly reduced dihydrotestosterone and epidermal growth factor levels in benign prostatic hyperplasia tissue, particularly in the periurethral zone, while Flutamide decreased epidermal growth factor but not dihydrotestosterone.
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    Research cited in this study 2

    1. The Effect of Finasteride in Men with Benign Prostatic Hyperplasia The New England Journal of Medicine · 1992
    2. Three-Month Treatment With a Long-Acting Gonadotropin-Releasing Hormone Agonist of Patients With Benign Prostatic Hyperplasia: Effects on Tissue Androgen Concentration, 5α-Reductase Activity and Androgen Receptor Content ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 1989

    Related research 2

    1. Prevalent Decrease of the EGF Content in the Periurethral Zone of BPH Tissue Induced by Treatment with Finasteride or Flutamide PubMed · 1997
    2. Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Serum Gonadotropins in Normal Men The Journal of Clinical Endocrinology and Metabolism · 1992