Comparative Evaluation of Superficial Cryotherapy Versus Intralesional Triamcinolone in Alopecia Areata at a Tertiary Care Center: A Dermoscopic and Clinical Study in Middle-Aged Adults

    November 2025 in “ The Journal of Medical Sciences ”
    Akhil Dadala, Priya KS, Lokanatha Keshavulu, Jagat Ram, Sai Priya Nagirimadugu
    New to Alopecia Areata? There is a guide in the encyclopedia. Read the guide →
    Image
    Studysummary This article reviews the potential and limitations of cryotherapy for alopecia areata in middle-aged patients and highlights the need for further research, without reporting new clinical findings. Our plain-language summary of this paper — not a Tressless recommendation.
    The study compares superficial cryotherapy and intralesional triamcinolone (ILT) for treating alopecia areata (AA) in middle-aged adults. AA is a chronic, immune-mediated disorder causing nonscarring hair loss, affecting 1-2% of the population. ILT is commonly used due to its anti-inflammatory effects, while cryotherapy is noted for its nonpharmacological immunomodulatory mechanism. The study highlights that cryotherapy, although outpatient-friendly and low-cost, generally has lower efficacy than ILT, especially in rapidly progressive or longstanding AA patches. The role of cryotherapy in middle-aged patients, who may have more stable immune profiles, remains underexplored.
    Discuss this study in the Community →

    Research cited in this study

    10 / 10 results