Measurement of Cortisol, Dehydroepiandrosterone, and Testosterone in the Hair of Children: Preliminary Results and Promising Indications

November 2018 in “ Developmental Psychobiology ”

Jesse Smith, Katherine A. Johnson, Sarah Whittle, Nicholas B. Allen, Julian G. Simmons

cortisol dehydroepiandrosterone testosterone DHEA

From the encyclopedia

a synthetic cortisol used for anti-inflammatory effects

Studysummary In this study, testosterone and dehydroepiandrosterone in children's hair were strongly correlated, supporting hair as a potential method for measuring these hormones.

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research LC-MS/MS-Based Method for Long-Term Steroid Profiling in Human Scalp Hair

134 citations , March 2015 in “Clinical Endocrinology”

This study introduced a validated LC-MS/MS-based method for profiling long-term steroid concentrations in human scalp hair, offering potential applications in endocrinology research.

research Validation and Reference Ranges of Hair Cortisol Measurement in Healthy Children

85 citations , January 2014 in “Hormone Research in Paediatrics”

This study found that hair cortisol concentrations can be reliably measured in healthy children and generally increase with age, unaffected by gender, puberty, or hair care practices.

research Maternal Influence on Child HPA Axis: A Prospective Study of Cortisol Levels in Hair

122 citations , October 2013 in “PEDIATRICS”

This study observed that cortisol concentrations in hair, indicating prolonged stress, are correlated between mothers and young children, suggesting potential heritable traits or maternal influence.

research An Investigation of Hair Cortisol Concentration Across Body Sites and Within Hair Shaft

22 citations , January 2010 in “Clinical Medicine Insights Endocrinology and Diabetes”

In this study, hair from forearms showed higher cortisol levels than hair from lower legs, suggesting a localized cortisol response in hair.

Hair as a Retrospective Calendar of Cortisol Production—Increased Cortisol Incorporation into Hair in the Third Trimester of Pregnancy

research Hair as a Retrospective Calendar of Cortisol Production—Increased Cortisol Incorporation into Hair in the Third Trimester of Pregnancy

501 citations , October 2008 in “Psychoneuroendocrinology”

This study suggests that cortisol measured in human hair can effectively reflect increased production for up to six months, but its retrospective accuracy may be limited due to rapid decline in levels.

research Measurement of Cortisol in Human Hair as a Biomarker of Systemic Exposure

567 citations , October 2007 in “Clinical and investigative medicine”

This study described a new assay for measuring cortisol in hair and found it may serve as a useful biomarker for long-term cortisol exposure, correlating with 24-hour urine cortisol levels in non-obese subjects.

research The Rise in Adrenal Androgen Biosynthesis: Adrenarche

173 citations , November 2004 in “Seminars in Reproductive Medicine”

This review discusses the physiological process of adrenarche, its impact on behavior and skeletal maturation, and its variability across sex and race, but reports no new clinical results.