Treatment of Chronic Prostatitis/Chronic Pelvic Pain Syndrome

    January 2008 in “ International Journal of Antimicrobial Agents ”
    J. Curtis Nickel
    TLDR Alpha-blockers are recommended first for recent CP/CPPS, while antimicrobials are not advised for long-term cases.
    The document reviewed the treatment of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) and highlighted the shift from traditional antimicrobial therapies to more evidence-based approaches. It concluded that antimicrobials were not recommended for men with longstanding CP/CPPS, while alpha-blockers were suggested as first-line therapy for those with recent onset and moderate symptoms. Anti-inflammatory therapy, finasteride, and pentosan polysulfate were not recommended as primary treatments but could be useful adjuncts. Herbal therapies like quercetin and cernilton showed promise, but larger trials were needed for conclusive recommendations. Surgery was advised only for definitive indications. The development of the NIH Chronic Prostatitis Symptom Index was pivotal in advancing research and treatment strategies.
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