Characterization of follicular minoxidil sulfotransferase activity in a cohort of pattern hair loss patients from the Indian Subcontinent
October 2018
in “Dermatologic Therapy”
TLDR About 41% of Indian hair loss patients have low enzyme activity that affects hair loss treatment effectiveness, with men affected more than women. Testing for this can guide treatment.
In 2018, a study of 120 pattern hair loss patients from the Indian subcontinent found that 40.8% had low levels of sulfotransferase activity, an enzyme that converts minoxidil, a common hair loss treatment, into its active form. Men had a higher percentage of low activity (49.3%) compared to women (26.6%). The study suggested that testing for sulfotransferase activity before starting therapy could help identify those who may not respond to minoxidil treatment and guide the prescription of the correct dosage for patients with androgenetic alopecia, the most common form of baldness.
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research Characterization of follicular minoxidil sulfotransferase activity in a cohort of pattern hair loss patients from the Indian Subcontinent
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