Study of the Association of Some Blood and Urine Markers in Diagnosing Pediatric Systemic Lupus Erythematosus

    September 2025 in “ Mansoura Journal of Chemistry
    Nourhan Mohamed Elhalaby, Omali Y. El‐khawaga, dram refaey, dalia tawfick
    TLDR Blood and urine markers are important for diagnosing lupus in children.
    This study investigated the association of blood and urine markers in diagnosing pediatric systemic lupus erythematosus (SLE) in children aged 5 to 18 years. The study found that SLE patients, predominantly female with an average age of 14.4 years, exhibited clinical symptoms such as fever, malar rash, bone discomfort, and alopecia. Significant hematological findings included reduced hemoglobin and leukocyte counts, while urinalysis showed elevated erythrocytes, leukocytes, and proteinuria, with 34% of patients experiencing varying degrees of proteinuria. These results highlight the importance of specific blood and urine markers in diagnosing juvenile SLE and suggest the need for further research to improve diagnostic criteria and patient outcomes.
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