Clinical Efficacy and Safety of Baricitinib in Patients With Alopecia Areata in Korea

    January 2025 in “ Annals of Dermatology ”
    Jae Won Lee, Hyun‐Tae Shin, Young Lee … Gwang Seong Choi
    Studysummary In this study, baricitinib was well tolerated and led to clinical improvement in patients with treatment-resistant alopecia areata in a real-world clinical setting, suggesting it may be a potential treatment option.
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    Research cited in this study 8

    1. Effectiveness and Safety of Baricitinib in Patients With Severe Alopecia Areata: A 36-Week Multicenter Real-World Experience Journal of Dermatological Treatment · 2023
    2. Real-Life Effectiveness and Tolerance of Baricitinib for the Treatment of Severe Alopecia Areata with 1-Year Follow-Up Data Dermatology and Therapy · 2023
    3. Efficacy and Safety of Baricitinib in Patients with Severe Alopecia Areata Over 52 Weeks in Phase III Trials American Journal of Clinical Dermatology · 2023
    4. Predominant Expression of Interleukin-17 in Chronic Alopecia Areata Compared to IFN-γ in Pathogenic Th17 Cells, Tissue-Resident Memory T Cells and Natural Killer Cells JEADV Clinical Practice · 2023
    5. Two Phase 3 Trials of Baricitinib for Alopecia Areata The New England Journal of Medicine · 2022
    6. The Alopecia Areata Investigator Global Assessment Scale: A Measure for Evaluating Clinically Meaningful Success in Clinical Trials British Journal of Dermatology · 2020
    7. Local Heroes or Villains: Tissue-Resident Memory T Cells in Human Health and Disease Cellular & Molecular Immunology/Cellular & molecular immunology · 2020
    8. Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition Nature medicine · 2014

    Related research 1

    1. Twenty Nail Dystrophy with Alopecia Areata in an Atopic Child International journal of research in dermatology · 2019