Axitinib-Induced Repigmentation of Grey Hair in a Patient With Metastatic Renal Cell Carcinoma
June 2025
in “
BMJ Case Reports
”
TLDR Axitinib treatment turned a man's grey hair back to black.
A 6-month axitinib treatment in a man with metastatic renal cell carcinoma led to the repigmentation of his grey hair, turning it black without any hair dye or other medications. Axitinib, a vascular endothelial growth factor receptor tyrosine kinase inhibitor, promotes melanogenesis, and while other TKIs have been linked to hair repigmentation, this is the first documented case involving axitinib.
