Axitinib-Induced Repigmentation of Grey Hair in a Patient With Metastatic Renal Cell Carcinoma

    June 2025 in “ BMJ Case Reports ”
    Avita Dhiman, Manju Daroach, Pravesh Dhiman
    Studysummary In this case report, researchers observed hair repigmentation in a man with metastatic renal cell carcinoma during treatment with axitinib, marking the first documented instance of this effect with axitinib without the use of hair dyes or other medications.
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    Research cited in this study 6

    1. Drug-Induced Hair Pigmentation: Clinical Perspectives and Updates JAAD reviews. · 2024
    2. Reversing Gray Hair: Inspiring the Development of New Therapies Through Research on Hair Pigmentation and Repigmentation Progress International journal of biological sciences · 2023
    3. Premature Graying as a Consequence of Compromised Antioxidant Activity in Hair Bulb Melanocytes and Their Precursors PLOS ONE · 2014
    4. Oxidative Stress in Aging of Hair International Journal of Trichology · 2009
    5. Hair Follicle Pigmentation: Mechanisms and Factors Influencing Melanin Production ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2005
    6. Tyrosine Kinase Inhibition and Grey Hair The Lancet · 2003