An Autopsy Case of Unicentric Castleman's Disease Associated with Bronchiolitis Obliterans
July 2014
in “
Respirology Case Reports
”
TLDR A woman with Castleman's disease died from respiratory failure due to bronchiolitis obliterans.
A 34-year-old woman presented with enanthema of the tongue, hair loss, and nonproductive cough, which partially improved with corticosteroids. She was diagnosed with unicentric, hyaline vascular type Castleman's disease after resection of a retroperitoneal mass. Despite treatment, she developed progressive dyspnea and was diagnosed with bronchiolitis obliterans. She died from respiratory failure, and autopsy revealed constrictive bronchiolitis and other pathological findings, confirming paraneoplastic autoimmune multiorgan syndrome associated with Castleman's disease.