Summary of an Audit of Clinical Trial Studies Conducted in the United States, Europe, Canada, and Australia for the Treatment of Various Types of Alopecia Over a Six-Year Period

David Barreto shared that a London-based research group is conducting a 12-month trial for a new nutraceutical treatment for pattern hair loss, designed with Dr. Carlos Puig. The trial aims to provide robust data, with results expected in 1-2 years, potentially representing a significant advancement since finasteride’s introduction in 1997.

The post discusses the completion of the HMI-115 Australian Phase 1 Trial for hair loss treatment. The user speculates about the potential early release of the trial results.

A 21-year-old male has been on a hair loss treatment for 6 months using finasteride, oral minoxidil, and ketoconazole shampoo, with slight improvement noted by his dermatologist. He is considering adding topical spironolactone, switching to dutasteride, increasing minoxidil dosage, or trying PRP injections for better results.

A 37-year-old man has been using a hair loss treatment for 11 weeks, including topical minoxidil, finasteride, tretinoin, dermastamping, and Nizoral shampoo, and is surprised by the progress, noting thicker and longer vellus hairs. He plans to continue and possibly escalate to oral treatments if needed, reporting no side effects so far.

The review discusses traditional hair loss treatments like minoxidil and finasteride, and newer options like Low-Level Laser Therapy, microneedling, and platelet-rich plasma for androgenetic alopecia. It highlights the need for more high-quality trials to assess these treatments' effectiveness and standardized protocols for emerging therapies.

Hair loss treatments include finasteride, minoxidil, microneedling, dutasteride, CB-03-01, RU-58841, and experimental options like KY-19382 and stem cell therapy. Some treatments are considered ineffective or risky, such as ketoconazole, PRP, and low-level laser therapy.