Antiparasitic Efficacy of Geraniol from Apiaceae Family in Scabies Treatment

May 2025 in “ Scientific Reports ”

Iman Khallaf, Lourin G. Malak, Soad A. L. Bayoumi, Salwa F. Farag, Ahmed M. Sayed, Sara A Mohamed, Asmaa A. E. Nasr, Radwa Y. Ibrahim, Eman Maher Zahran, Gerhard Bringmann, Usama Ramadan Abdelmohsen

geraniol Apiaceae family acaricidal activity scabies mite mortality in vitro in vivo synthetic acaricides

Studysummary This study found that geraniol, derived from Apiaceae plants, may be an effective and eco-friendly treatment for scabies, achieving complete clinical recovery in infected rabbits within two weeks. Our plain-language summary of this paper — not a Tressless recommendation.

The study explores the antiparasitic efficacy of geraniol, a compound from the Apiaceae family, in treating scabies. Geraniol showed strong acaricidal activity, achieving 100% mite mortality at a 6.25% concentration within 15 minutes in vitro. In vivo tests on 20 scabies-infected rabbits demonstrated complete clinical recovery and new hair growth within two weeks, with no adverse effects. These findings suggest that geraniol is a promising, safe, and eco-friendly alternative to synthetic acaricides, though further research is needed to explore delivery systems and conduct human clinical trials.

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Scabicidal Potential of Coconut Seed Extract in Rabbits via Downregulating Inflammatory/Immune Cross-Talk: A Comprehensive Phytochemical/GC-MS and In Silico Proof

research Scabicidal Potential of Coconut Seed Extract in Rabbits via Downregulating Inflammatory/Immune Cross-Talk: A Comprehensive Phytochemical/GC-MS and In Silico Proof

9 citations , December 2022 in “Antibiotics”

This study found that coconut seed extract may effectively treat scabies in rabbits by improving infection signs and causing high mite mortality, suggesting its potential as a cost-effective herbal alternative.