Effect of Antioxidant Supplementation on Digestive Enzymes in Radiation-Induced Intestinal Damage in Rats
July 2013
in “
International Journal of Radiation Biology
”
New to Vitamin E? There is a guide in the encyclopedia. Read the guide → Studysummary In this study, antioxidant vitamins A, C, and E were found to help protect against intestinal damage caused by radiation in rats, with vitamin E being the most effective.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
The study investigated the effects of antioxidant vitamins on radiation-induced intestinal damage in Swiss Albino rats. Rats were divided into six groups, with one control group and five irradiated groups, each receiving different antioxidant supplements (vitamin A, C, E, or lycopene). Radiation exposure led to gastrointestinal toxicity, including malabsorption, diarrhea, weight loss, and hair loss, with altered activities of digestive enzymes. Antioxidant vitamins, particularly vitamin E, were effective in preventing changes in enzyme activities and minimizing intestinal damage, as evidenced by improved intestinal histology. The study concluded that antioxidant vitamin supplementation, especially vitamin E, was beneficial in reducing radiation-induced intestinal damage.
