TLDR Androgenetic alopecia causes hair loss, affects men more severely, and treatments are only temporarily effective.
Androgenetic alopecia (AGA) was the most common type of alopecia affecting both men and women, with a more severe and frequent impact on men. The condition was characterized by a progressive loss of hair diameter, length, and pigmentation, and was believed to develop in genetically susceptible individuals due to androgens. Although several treatment options were available, the therapeutic effects of drugs were found to be only temporary. The psychological and social impacts of AGA were more significant in women.
September 2017 in “Journal of Investigative Dermatology” BMPs are crucial for hair growth and their decrease by androgens leads to hair loss.
153 citations
,
March 2017 in “Endocrine” Male pattern baldness involves genetics, hormones, and needs better treatments.
7 citations
,
September 2020 in “Journal of Cosmetic Dermatology” Serum biomarkers like insulin-like growth factor-1 and vitamin D may help diagnose androgenetic alopecia.
Bone Morphogenetic Proteins (BMPs) are important for hair growth, and their decrease due to hormones could lead to hair loss, but adding more BMPs could promote hair growth.
52 citations
,
June 2009 in “Current Opinion in Endocrinology, Diabetes and Obesity” The document concludes that hair transplantation and gene therapy may be important for future hair loss treatment.
September 2019 in “Journal of Investigative Dermatology” BMPs are important for hair growth and can counteract the negative effects of androgens on hair follicle stem cells.
