Alopecia Areata: Physiological Aspects And Therapeutic Advances – A Literature Review

    November 2024 in “ Revista fisio&terapia.
    A. Rosa, María Santiago, Suelen Caroline de Souza Andrade, Sabrina de Souza, Cínthia Silva Moura Neca, Adriano da Silva
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    Studysummary This literature review found that among therapies for Alopecia Areata, Janus kinase inhibitors are particularly promising despite safety challenges, while newer approaches like stem cells face cost and complexity issues; a comprehensive approach integrating medical and emotional support was emphasized for improving patient outcomes.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    Alopecia Areata is an autoimmune condition causing hair loss, with current treatments like immunosuppressants, corticosteroids, and JAK inhibitors showing variable efficacy. JAK inhibitors are promising but face safety and accessibility issues. Emerging therapies, such as stem cells and biological medicines, are promising but limited by cost and complexity. The review emphasizes the importance of a multidisciplinary approach, combining clinical treatment with emotional support, to improve patient quality of life. It calls for further research to refine existing therapies and explore new, effective, and accessible treatment options, considering the complex interplay of genetic and environmental factors in disease progression.
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