A Scoping Review of Alopecia Areata and Its Relationship to COVID-19 Vaccinations

This scoping review examines the potential link between COVID-19 vaccinations and alopecia areata (AA). Despite some reports of AA following vaccination, especially in those with a history of AA or autoimmunity, the review finds no evidence of an increased incidence of AA due to COVID-19 vaccines. The analysis, which includes 26 case reports, 1 prospective study, and 3 retrospective chart reviews, indicates no significant difference in AA incidence between vaccinated individuals and historical controls. The review concludes that the risk of developing AA post-vaccination is low, and the benefits of COVID-19 vaccination outweigh the risks. While factors like female sex and a history of autoimmunity may increase susceptibility to AA, they should not discourage vaccination. Further research is suggested to explore the mechanisms behind vaccine-related AA.