Original Article: Alcohol Exposure During Late Adolescence Increases Drinking in Adult Wistar Rats, an Effect That Is Not Reduced by Finasteride

The study investigated the effects of alcohol exposure during late adolescence on drinking behavior in adult Wistar rats and examined whether finasteride could mitigate these effects. The results indicated that adolescent alcohol exposure led to increased alcohol consumption in adulthood. However, the administration of finasteride, a 5α-reductase inhibitor, did not reduce this increased drinking behavior. This suggested that the mechanisms by which adolescent alcohol exposure influenced adult drinking were not mediated by pathways affected by finasteride. The study provided insights into the long-term impacts of adolescent alcohol exposure on drinking behavior, although it did not specify the number of rats involved in the study.