Acne Tarda: Prevalence, Endocrine Correlation, Therapeutic Measures

    Sofia Sarah Rotshtein
    From the encyclopedia
    Spironolactone →

    powerful topical and oral anti-androgen used mostly by women

    Azelaic Acid →

    acid used for antimicrobial, anti-inflammatory and anti-androgenic properties

    Studysummary This study found that acne tarda is prevalent, particularly among women and individuals with darker skin, with hormonal imbalances and endocrine disorders like PCOS commonly associated with its pathogenesis.
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    The study systematically reviewed the prevalence, therapeutic approaches, and endocrine correlation of acne tarda, finding it more common in women and individuals with darker skin tones. Hormonal imbalances, particularly involving androgens, significantly contribute to its pathogenesis, with conditions like PCOS often associated. Treatment should be tailored to severity: topical retinoids for mild cases, systemic treatments for moderate to severe cases, and hormonal therapies and spironolactone showing high efficacy in adult female acne. Isotretinoin is crucial for severe nodular cystic acne, and maintenance therapy with topical retinoids and azelaic acid is important to prevent relapse.
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