Exact, Time-Independent Estimation of Clone Size Distributions in Normal and Mutated Cells

    Amit Roshan, Philip H. Jones, Chris Greenman
    Studysummary This study demonstrates that modeling clone size independently of time offers analytical advantages for understanding cell distribution and mutation frequency in epithelial progenitors, extending applications beyond neutral models.
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    Research cited in this study 2

    1. Live Imaging of Stem Cell and Progeny Behavior in Physiological Hair-Follicle Regeneration Nature · 2012
    2. Identification of the Cell Lineage at the Origin of Basal Cell Carcinoma Nature Cell Biology · 2010