Elucidation Of Stem Cell Formation Mechanism By Fibroblast Aggregates

This study found that cell spheres formed from mesenchymal cells in newborn mouse skin showed increased expression of genes associated with hair follicle regeneration, though marker distribution varied and requires further investigation.

This study observed that cell aggregates derived from mouse skin and lung tissues may aid in hair follicle regeneration when transplanted into skin defects of immunodeficient mice.

This study found that transplanting cell aggregates from mouse skin and lung mesenchymal cells can regenerate hair follicles in immunodeficient mice with skin wounds.

This study provided a dynamic 4D atlas showing the development process of mouse hair follicles through a telescope-like model, revealing new insights into the origin of hair follicle stem cells.

This study found that hair follicle patterning in development may arise from a combination of epidermal prepattern signals and mesenchymal self-organisation, with fibroblast growth factor and bone morphogenetic protein activities playing key roles.