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    The Impact of Metformin on Plasma Prolactin Levels in Antipsychotic-Treated Men With Hyperprolactinemia and Early-Onset Androgenic Alopecia

    May 2025 in “ Clinical Endocrinology ”
    Robert Krysiak, Karolina Kowalcze, Marek Krzystanek … Bogusław Okopień
    Studysummary In this study, metformin was found to reduce prolactin levels in men with hyperprolactinemia and normal hair growth but not in those with androgenic alopecia, suggesting that androgen excess may interfere with metformin's effects on prolactin.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 9

    1. Factors Associated With Early-Onset Androgenetic Alopecia: A Scoping Review PLOS ONE · 2024
    2. Impaired Prolactin-Lowering Effects of Metformin in Women with Polycystic Ovary Syndrome Journal of Clinical Medicine · 2023
    3. Impaired Cardiometabolic Effects of Bromocriptine in Men With Early-Onset Androgenic Alopecia The Journal of Clinical Pharmacology · 2022
    4. Pituitary Effects of Metformin in Men With Early-Onset Androgenic Alopecia The Journal of Clinical Pharmacology · 2022
    5. Impaired Metabolic Effects of Metformin in Men with Early-Onset Androgenic Alopecia Pharmacological Reports · 2021
    6. Male Equivalent Polycystic Ovarian Syndrome: Hormonal, Metabolic, and Clinical Aspects DOAJ (DOAJ: Directory of Open Access Journals) · 2020
    7. Androgenetic Alopecia: A Review Endocrine · 2017
    8. A Comparison of the Hormonal Profile of Early Androgenetic Alopecia in Men With the Phenotypic Equivalent of Polycystic Ovarian Syndrome in Women JAMA Dermatology · 2016
    9. Androgenetic Alopecia: An Update Indian Journal of Dermatology, Venereology and Leprology · 2013