Macrophages Are Necessary for Skin Regeneration During Tissue Expansion

January 2019 in “ Journal of Translational Medicine ”

Jinli Ding, Lei Lei, Shiqiang Liu, Yu Zhang, Yu Zhang, Yingjun Su, Xin Ma

macrophages skin regeneration tissue expansion cell proliferation collagen synthesis vascularization growth factor secretion M1 macrophages M2 macrophages

Studysummary This study found that macrophages are crucial for skin regeneration during tissue expansion, as their depletion in rats led to inhibited skin growth and reduced secretion of key growth factors.

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