Histological Analysis of the Impact of Isotretinoin on Endochondral Ossification in Wistar Rats

    January 2015
    Flávio Paccelli, Silva Sento, Huggo Luãn, Barros Medeiros, Thiago de Oliveira Assis
    Studysummary In this study, isotretinoin treatment in young male Wistar rats was associated with delayed ossification, supporting earlier reports of potential bone malformations from the drug.
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