January 2023 in “BOĞAZİÇİ TIP DERGİSİ” This study found that female adolescents with pilonidal sinus disease had significantly higher insulin levels and HOMA-IR scores, suggesting hyperinsulinemia may be a risk factor for the condition.
June 2023 in “Medical records-international medical journal” This study observed that IGF-1R expression significantly decreased in basal keratinocytes of sacrococcygeal pilonidal sinus tissues, suggesting a potential role in its etiology, although further data are needed to evaluate its treatment implications.
June 2019 in “Journal of Akhtar Saeed Medical & Dental College” This study found that while serum prolactin levels were higher in women with hirsutism, the relationship between prolactin levels and hirsutism severity was not statistically significant.
September 2023 in “Acta dermato-venereologica” This study found that pilonidal sinus disease is a common comorbidity with hidradenitis suppurativa and is linked with increased disease severity, suggesting it may serve as a sentinel event for identifying high-risk patients.
October 2024 in “Journal of Medical and Scientific Research” This study found that serum prolactin levels were significantly higher in patients with psoriasis, alopecia areata, and vitiligo compared to healthy controls, and prolactin levels were also correlated with disease severity in psoriasis and alopecia areata patients.
