Sigma-1 Receptor-Related Neuroactive Steroids Modulate Cocaine-Induced Reward

    May 2003 in “ Journal of Neuroscience ”
    Pascal Romieu, Rémi Martin‐Fardon, Wayne D. Bowen, Tangui Maurice
    Studysummary This study found that neuroactive steroids like DHEA and pregnenolone influence cocaine-induced appetence in mice through their interaction with the ς<sub>1</sub> receptor, suggesting a role in individual vulnerability to addiction.
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