Differentiation of Human Hair Follicle Stem Cells Into Endothelial Cells Induced by Vascular Endothelial and Basic Fibroblast Growth Factors
November 2013
in “
Molecular Medicine Reports
”
New to Vascular Endothelial Growth Factor? There is a guide in the encyclopedia. Read the guide → Studysummary This study demonstrated that human hair follicle stem cells can be efficiently differentiated into endothelial-like cells using VEGF and bFGF, suggesting their potential as a novel cell source for vascular tissue engineering.
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The study demonstrated that human hair follicle stem cells (hHFSCs) could be efficiently differentiated into endothelial cells (ECs) using vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF). The differentiated cells expressed EC-specific markers and were capable of low-density lipoprotein uptake, indicating their functionality as ECs. This suggested that hHFSCs could be a novel and accessible cell source for vascular tissue engineering and potential treatments for ischemic vascular diseases.
