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    Tofacitinib Treatment in a Severe Pediatric Alopecia Areata: A Case Report and a Literature Review

    January 2024 in “ Skin Research and Technology ”
    Dongmei Shi, Wei Wang, Dongmei Shi
    Studysummary This case report found that oral tofacitinib treatment resulted in more than 90% hair regrowth in a 6-year-old with severe alopecia areata, with no relapse after dose reduction.
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    Research cited in this study 7

    1. Alopecia Areata Flare Patterns in Children and Young Adults on Systemic Tofacitinib Journal of the American Academy of Dermatology · 2021
    2. Tofacitinib Therapy for Children with Severe Alopecia Areata Journal of the American Academy of Dermatology · 2019
    3. Tofacitinib for the Treatment of Alopecia Areata in Preadolescent Children Journal of the American Academy of Dermatology · 2018
    4. Experience with Oral Tofacitinib in 8 Adolescent Patients with Alopecia Universalis Journal of the American Academy of Dermatology · 2017
    5. JAK Inhibitors in Dermatology: The Promise of a New Drug Class Journal of the American Academy of Dermatology · 2017
    6. Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition Nature medicine · 2014
    7. Alopecia Areata Update Journal of The American Academy of Dermatology · 2010

    Related research 4

    1. Resistant Alopecia Areata Treated with Tofacitinib International Journal of Trichology · 2022
    2. Successful Treatment of Severe Alopecia Areata With Oral or Topical Tofacitinib PubMed · 2018
    3. Topical Minoxidil for the Treatment of Alopecia Areata PubMed · 2017
    4. Effectivity of Minoxidil as a Treatment for Alopecia Areata DOAJ (DOAJ: Directory of Open Access Journals) · 2013