Alopecia Areata in Twins With Autoimmune Thyroiditis: Personal Observations

July 2019 in “ Dermatology practical & conceptual ”

Giusy Schipani, Stefano Dastoli, Elisabetta Scali, Luigi Bennardo, Martina Silvestri, Steven Paul Nisticò

alopecia areata autoimmune thyroiditis betamethasone vasodilatory lotions antiseptic lotions autoantibody dermatological manifestations AA thyroiditis steroid scalp lotion

From the encyclopedia

Alopecia Areata →

autoimmune disorder causing patchy hair loss

Betamethasone →

Studysummary This report presents personal observations of alopecia areata in twins with autoimmune thyroiditis and suggests a possible link, though it does not provide new clinical results.

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Research cited in this study

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research Alopecia Areata: A Review of Disease Pathogenesis

191 citations , May 2018 in “British journal of dermatology/British journal of dermatology, Supplement”

This study reviewed recent theories on alopecia areata's pathogenesis, highlighting its autoimmune nature due to immune privilege disruption in hair follicles, and noted current treatments have limited efficacy with high relapse rates, underscoring the need for further research into its mechanisms for better therapies.

research Alopecia Areata: A Comprehensive Review of Pathogenesis and Management

99 citations , July 2017 in “Clinical Reviews in Allergy & Immunology”

This review noted that alopecia areata is an autoimmune disease impacting hair follicles and offered insights into its complex pathogenesis involving immune responses, while highlighting ongoing research into new treatments such as Janus kinase inhibitors and other immunomodulatory drugs.

research Endocrine Controls of Primary Adult Human Stem Cell Biology: Thyroid Hormones Stimulate Keratin 15 Expression, Apoptosis, and Differentiation in Human Hair Follicle Epithelial Stem Cells In Situ and In Vitro

42 citations , July 2010 in “European Journal of Cell Biology”

This study found that thyroid hormones T3 and T4 enhance keratin 15 promoter activity and stimulate CD200 expression in epithelial stem cells from human scalp hair follicles, affecting their growth and differentiation.