Betamethasone Activates Cultured Amelanotic Melanocytes Derived From Outer Root Sheath of Human Hair Follicle

January 2008 in “ Linchuang pifuke zazhi ”

LI Cheng-rang

New to Betamethasone? There is a guide in the encyclopedia. Read the guide →

betamethasone amelanotic melanocytes outer root sheath human hair follicle TYR TRP-1 TRP-2 tyrosinase activity melanin content glucocorticoid treatment vitiligo BT AMMC

Studysummary This study found that betamethasone increased tyrosinase activity and melanin content in amelanotic melanocytes from human hair follicles, suggesting a potential mechanism for glucocorticoid treatment in vitiligo.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer ·

View this study on en.cnki.com.cn →

Discuss this study in the Community →

Similar Research

5 / 1000+ results

research Culture of amelanotic melanocytes derived from human fetal hair follicles

2 citations , June 2013 in “In Vitro Cellular & Developmental Biology - Animal”

This study successfully cultured human fetal hair follicle-derived melanocytes, which showed high proliferative capabilities and unique morphological characteristics compared to adult-derived cells, potentially advancing hair disease research.

research Location and fine structure of melanocytes in human fetal scalp hair follicles.

March 2009 in “Chinese Journal of Dermatology”

This study observed that melanocytes in the outer root sheath of fetal scalp hair follicles may act as stem cells, showing rapid proliferation but immature function and morphology in culture.

research Culturing of Melanocytes from the Equine Hair Follicle Outer Root Sheath

1 citations , January 2021 in “Processes”

This study adapted a method for culturing melanocytes from human hair follicles to horses, successfully creating partially melanotic equine melanocytes, potentially advancing hair follicle biology research across species.

research Observation of cultured amelanotic melanocytes from hair follicles by atomic force microscopy

January 2006 in “Chinese Journal of Dermatology”

This study observed that amelanotic melanocytes from human hair follicles appeared morphologically immature, suggesting they might not transfer melanosomes into keratinocytes.

research Morphologic comparison of cultured human epidermis melanocytes,amelanotic melanocytes from hair follicles and mouse melanoma cells observed by atomic force microscope

January 2003 in “Linchuang pifuke zazhi”

This study used atomic force microscopy to image surface structures of human epidermal melanocytes, hair follicle amelanotic melanocytes, and mouse melanoma cells, revealing differences in branch structure and granule distribution.