Comparative Studies of Specific Activity of Soft Dosage Forms of Minoxidil for Trichological Practice
March 2023
in “
The Scientific Issues of Ternopil Volodymyr Hnatiuk National Pedagogical University Series pedagogy
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Studysummary In this study, new formulations of 2% minoxidil cream and a minoxidil shampoo with plant antioxidants showed significant hair growth-stimulating and follicle-protective effects in an experimental alopecia model.
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The study conducted by Zaporizhzhia State Medical University evaluated two new topical minoxidil formulations—a 2% cream and a 1% gel-based shampoo—designed to treat androgenic alopecia. The research demonstrated that both formulations exhibited significant hair growth-stimulating and follicle-protective activities in experimental alopecia models. The 2% minoxidil cream showed a comparable growth-stimulating effect to the reference spray "Pilfood Bosnalek," while the "Trichlomine" shampoo outperformed the reference "Dove" shampoo in stimulating hair growth. The shampoo's enhanced effect was attributed to its plant-antioxidant complex, which potentiated minoxidil's action. However, neither the cream nor the reference products significantly impacted dermal energy metabolism indicators.