Adverse Reaction to Isotretinoin: Alteration of the Hair Shaft Structure

Isotretinoin and tretinoin are different; isotretinoin can cause hair loss and has more side effects. Tretinoin may affect minoxidil absorption, and users suggest waiting before applying minoxidil.

The conversation discusses using isotretinoin (Accutane) to reduce scalp oiliness and manage scalp issues like seborrheic dermatitis, inflammation, and chronic itch. A user shares that taking 20mg of Accutane every other day effectively reduces oily hair and skin.

Topical retinol does not affect hair loss and may help hair regrowth. It is different from isotretinoin, which can cause hair loss due to its systemic effects.

Accutane can cause hair thinning in some users, with effects varying from no change to permanent hair loss. Some users reported improvements in hair and skin with treatments like Finasteride, while others experienced severe side effects, including mental health issues.

Mixing tretinoin gel with Minoxidil for hair application is discussed, with suggestions to mix per application to avoid clogging and degradation. Some users apply tretinoin cream to the hairline and use Minoxidil and finasteride, noting potential irritation on the crown.

Pyrilutamide's effect on sebum production and scalp inflammation is unclear, with users noting no significant changes. Isotretinoin is mentioned as effective for reducing sebum, while Dutasteride and various shampoos have limited impact on oiliness and seborrheic dermatitis.